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Adult patients are eligible for ART if they have a positive HIV test, understand the implications of therapy, and are assessed in WHO clinical stage 3 or 4 or have a CD4-lymphocyte count <250 cells/mm3 [5], [5].
Even an average mortality rate is helpful in explaining the implications of therapy to individual patients, as well in calculating the economic implications of prescribing policies.
During the period of this evaluation, patients were eligible for first-line ART if they were HIV-infected, understood the implications of therapy, and fell into one of these three categories: patients in WHO clinical stage IV, patients in WHO clinical stage III with CD4 count less than 350 cells/dl, or all patients with CD4 count less than 200 cells/dl regardless of clinical criteria [ 12].
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Furthermore, there has been little consideration of patients and parents' perceptions regarding the impact of complementary therapies on asthma and the implications of complementary therapy use for NHS asthma care.
In light of the fact that there is currently no available therapy to slow or halt the pathological progression of PD, the potential therapeutic implications of a therapy targeted at the mechanism responsible for the transmission of pathology from one region to another are formidable.
Solban, N. et al. Mechanistic investigation and implications of photodynamic therapy induction of vascular endothelial growth factor in prostate cancer.
The development of maintenance therapy has raised issues about the role of treatment-free intervals in routine clinical care, trial design issues such as the optimal endpoint, the ethics of a placebo arm, and the implications of maintenance therapy for first-line trials.
Jeff Lyon and Peter Gorner of the Chicago Tribune won the explanatory journalism prize for their series examining the implications of gene therapy as a revolutionary medical treatment.
Preoperative seizure control and the implications of anticonvulsant therapy warrant a mention.
The economic implications of combination therapy depend to some extent on the characteristics of the cohort analyzed.
Future studies of newer agents with less severe side effects and studies of clinicopharmacologic implications of drug therapy in older patients are indicated.
More suggestions(16)
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