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The potential functional implications of the variation in these genes are currently unknown.
Future plans include increased integration of additional annotation data that assess the functional implications of the variation, including but not limited to intersection of SNP locations with known or predicted functional elements such as splice sites, promoter elements, and polyadenylation sites or overlap with regions of evolutionary conservation, such as provided by the PhastCons scores (21).
To get an impression from the clinical implications of the variation in SCr values on CKD staging, we classified the patients according to the K/DOQI guidelines and evaluated the differences in CKD staging when SCr values were measured by Jaffe or the enzymatic methods [ 18].
In contrast to the lack of knowledge about implications of the variation in exon 4, the variable sites in ECL3 and 4 have been shown to be determinants for virus entry or to modulate virus interaction [ 22, 40, 57, 59, 60].
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Explanations for and implications of the variations are discussed.
In section 4.4.5 we discuss the implications of the variations based on loop-directed mutagenesis results.
We did not explore the cost implications of the variations in staffing observed.
However, because the CNV analysis does not distinguish between genes and pseudogenes, and there is an RBMY pseudogene located at 9,148,467 9,162,451 (which contains only a single probe and thus does not permit reliable CNV measurement), the biological implication of the variation detected remains uncertain.
Nor is there sufficient knowledge on the implications of these variations for the health of the environment and its ecosystems.
We show how widely these elements vary across five different assessments and discuss the implications of this variation.
We also explore the implications of this variation in light of particular interdisciplinary learning objectives.
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implications of the modification
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the effects of the variation
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