Sentence examples for implications of the structural from inspiring English sources

We also expand upon the implications of the structural findings to the structure and function of the eukaryotic clamp loader, RFC, and the structure of E. coli DNA polymerase III holoenzyme.

We discuss the implications of these structural observations for the catalytic mechanism of PNPase, its processive mode of action, and its assembly into the RNA degradosome.

Finally, we will discuss the implications of these structural findings for the development of antiviral drugs to treat human diseases caused by members of the Bunyaviridae and Arenaviridae families.

We discuss the implications of these structural data for the enzyme reaction mechanism.

Finite-element models have demonstrated that core drilling of a lesion could have major implications for the structural integrity of the head (Brown et al. 1993).

The failure mode for edifice host rock has attendant implications for the structural stability of the edifice and the efficiency of the sidewall outgassing of the volcanic conduit.

Furthermore, the implications of this structural information for drug screening and structure-based drug design will be discussed.

We discuss the recent discovery that CpG methylation increases DNase I cleavage at adjacent positions by an order of magnitude through altering the local 3D DNA shape and the possible implications of this structural insight for understanding the methylation sensitivity of transcription factors (TFs).

We therefore suggest that these differences in gene targeting likely represent a sexually-dimorphic disease-related re-wiring of the cellular network and that understanding the biological implications of these structural changes may provide insight into the mechanisms driving disease morphology and lead to suggestions for sex-specific therapies.

We examine the possible implications of these structural insights for understanding the methylation sensitivity of transcription factors (TFs).

However, the potential influence of structural molecular constraints on the evolution of complexity is only just starting to be understood (Prendergast and Semple, 2011; Fernández and Lynch, 2011; Chambers et al., 2013), and the implications of these structural and mechanistic constraints for evolutionary models must still be investigated in depth.