Our results unravel a complex metal-regulation system involving 3 distinct DMTs coordinately regulated by metal levels, and bear interesting implications on the modulation of the vertebrate DMT activities carried out by NRAMP1 and DMT1 isoforms.
This data has implications for the modulation of redox states in cancer stem cells, which are thought to be resistant to therapy due to their low ROS states.
The effect of age and the implications of this modulation for tissue repair was investigated.
The implications of the compositional modulation on key process parameters are discussed.
These data show how PARP-1 inhibition has strong metabolic implications through the modulation of SIRT1 activity, a property that could be useful in the management not only of metabolic diseases, but also of cancer.
Clinical implications regarding the modulation of positive imagery after a positive emotional experience are discussed.
Are there potential clinical implications regarding the modulation of positive imagery after a positive emotional experience?
It should also be noted that the profound biomedical implications associated with the modulation of hepcidin pathways render the hepcidin ferroportin axis an attractive target for drug development.
The results reported by Shaeffeler et al. [ 4] also highlight the clinical implications of epigenetic modulation of transporter expression.
P value for interaction = 0.038 The PPARD receptor has a well established role in lipid metabolism, but its implication in the modulation of lipid stores is more controversial.
