In any case, further functional studies are required to unequivocally prove the implication of the candidate gene in controlling the proposed volatile accumulation.
However, we are aware that, given the small sample size for which CGH and transcriptomic data were available, this genomic exploration only provides leads for functional analyses to formally demonstrate the implication of the candidate drivers in GC tumorigenesis.
Although the implication of these candidate genes is only a preliminary finding, and validation by microsatellite analysis in a larger cohort of samples would be required in order to definitively link them with the pathogenesis of NHL, they clearly illustrate the utility of the CHC method for derivation of LOH candidates.
To explore implications of highlighted candidate genes in adiposity, we focused on two mouse models, including strains highly variable for obesity-related phenotypes.
The Electoral Implications of Candidate Ambiguity.
If true, addressing his brother as "Kennard" (not "Dr. Clark") while introducing himself as "Gen. Wesley Clark" (rather than "Wesley" or "Wesley Clark") says a number of things about Clark, the man (and by implication, the candidate) -- and none of it is flattering.
Thus, it is crucial to examine more deeply the implications of candidates' stated faith-based positions, keeping in mind the Constitution's prohibition against religious tests in government.
Furthermore, we must not underestimate the importance of the candidate countries being involved for the first time in an institutional process that has constitutional implications.
Other candidates kept their focus on the implications of the Paris attacks for immigration policy.
