Nevertheless, we do detect a genome-wide pattern of strong, but incomplete, interference with some observed variation in the strength of interference among chromosomes; these results have important implications for the analyses of genomic data (see below).
We also discuss the importance of a new publicly available and extensively curated database PDmutDB, and the implications of these analyses for mutation analyses in a diagnostic setting.
Consequently, as a result of using unadjusted values, a conservative approach should be used for interpreting the implications of these analyses.
Furthermore, given the small sample size, we are unable to make any firm conclusions about the clinical implications of these analyses.
Accordingly, we recommend that you remove or truncate the speculation on the implications of the MVPA analyses (e.g. the comparison of HF vs PHC), which is difficult to interpret because of the large differences between the 'dissimilar' task conditions.
The implications of the sieve analyses along with immunologic and viral data suggest that both positions 169 (V2) and 307 (V3) are subject to immune pressure by RV144-induced Abs that target 169 (Liao et al., 2013, Zolla-Pazner et al., 2013) and 307 (XP Kong, personal communication and Montefiori et al., 2012).
The purpose of this study is to summarize results and implications of these analyses.
Implications of these analyses relating to streamflow predictions and model calibration are also discussed.
The most critical implication of these analyses is that it is entirely plausible that the MRCA of the sample could be alive as early as the spring of 2002.
We discuss the implications of our analyses for the as yet unresolved structure of the full-length A3G protein and its biological functions with regard to hypermutation of DNA.
