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In this way, Epi4K will be able to leverage its established clinical resources not only for discovering susceptibility variants, but also for exploration of the prognostic implications of susceptibility variants.
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In this regard, implication of susceptibility to environmental factors has been reported for function of the Gsdm family genes.
It can be argued that sharing of CNVs between more than two individuals in the same family should be used for identification of CNV with major implications on susceptibility for BPD.
In this article we start from the assumption that for a better understanding of the future ethical implications of genetic susceptibility screening we need to address the interaction between technological and moral developments in society.
The implications of this susceptibility to spoofing [ 19– 21]—defeating a biometric system through fake biometric samples include the following [ 22].
As long as uncertainty prevails regarding the psychological implications of genetic susceptibility testing for psychiatric diseases, a cautious approach may be warranted, even in consenting adults.
It is known that environmental factors can affect fetal life and may have long-term implications for susceptibility or resistance to infections [14], development of metabolic syndromes and cardiovascular diseases [15] [17], or asthma and allergy [18].
The implication of MLO susceptibility proteins in other physiological processes would explain why, in spite of being required for pathogenesis, they have been not excluded by evolution.
Changes of particular interest include three sets indicating altered JNK activity, which may have implications for susceptibility to apoptosis.
Interestingly, this analysis revealed several SNPs with implications for susceptibility to cancer and cardiovascular diseases.
These scenarios involve the implications of increased host susceptibility to endotoxin stimulus followed by systematic perturbations in the regulatory signaling module.
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CEO of Professional Science Editing for Scientists @ prosciediting.com