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Computational approaches to predicting function may need to be incorporated into clinical decision support methods in trying to determine the implications of such variants for clinical care.
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In this study we aimed to elucidate RANK regulation at the post-transcriptional level through alternative splicing, and further investigate the functional implications of the existence of such variants on the RANK/RANKL pathway.
MRCP can assist detection of such variants when suspected clinically.
Speakers on the second day grappled with the uncertainty and implications of finding such variants on a medical, ethical and legal level.
The implication of such discrepancy needs to be discussed.
The implications of such widespread genetic copy number variation on phenotypic variation are as yet uncertain, but some copy number variants clearly have a functional effect.
Consider the implications of such a comment.
The implications of such snooping are obvious.
The implications of such research are huge.
The implications of such findings are broad and worrisome.
The implications of such a charge are explosive.
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