Sentence examples for implications of blocking from inspiring English sources

The safety implications of blocking the human cardiac Na+ channel (hNav1.5) make it prudent to test for this activity early in the drug discovery process and design-out any potential liability.

It is not only the presence of drug target, but also the functional implications of blocking the target that are important.

33 Davis et al studied the effects of ibrutinib in different types of lymphoma cell lines in order to evaluate the implications of blocking BCR signaling in diffuse large B cell lymphoma and the relationship with the signaling adaptor CARD11.

Understand the implications of blocking someone.

The health implications of blocked and overflowing sewers are obvious.

Additional research is therefore warranted to study the potential influence of blocking on virus transport and potential implications for MAR guidelines.

Our work may have important implications in nanomedicine, for the development of vaccines and antiadhesion molecules capable of blocking the pilus activity.

These findings may have therapeutic implications in the treatment of patients with severe systemic manifestations after snakebites in terms of the possible benefits of blocking TNF activity.

Evaluation of compounds in an integrated biological system (e.g. animal-based models) is often a key to understanding the implications of multichannel block.

We discuss the implications of the gene block arrangements and block fragmentation patterns discerned in this study to the evolutionary relationship of A and B genomes.

It is useful to speculate on the potential financial implications of nearly eliminated neuromuscular blocking agent use, reduced sedative use, and diminished pressor use.