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There is increasing awareness of the implications of altered PK during critical illness in adult patients [ 19- 21].
The implications of altered gene expression in blood leukocytes are unknown, and this measure has not been validated as a surro-gate measure of effects on hormone-responsive gene expression.
This review focuses on how this dynamic function is achieved and discusses the implications of altered Atg7-mediated autophagic activities in molecular, cellular, and organismal levels.
However the potential implications of altered Rh splicing in SCD is still unclear.
In this review and analysis, we evaluate the use of HRV monitoring to provide early diagnosis of infection, document the prognostic implications of altered HRV in infection, identify current limitations, highlight future research challenges, and propose improvement strategies.
Our discussion of the implications of altered miRNAs in the carcinogenic risk of RDX suggested by a previous study (Lish et al. 1984) are based on the knowledge that aberrant miRNA expression is associated with a broad range of cancers (Zhang et al. 2007).
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Thomas has argued that there has been little discussion of the ethical and cultural implications of altering nature so fundamentally.
Design of CRPC trials is still strongly debated 26 and therefore the implications of altering the disease progression criterion were evaluated.
The other main limitation of the present study is that d-serine itself was not measured, even though most of the functional implications of altering DAO and SRR expression are implicitly or explicitly the result of their effect upon d-serine levels.
The implication of altered TLR responsiveness to endotoxin in HIV infection is substantive.
As highlighted by the authors in the Introduction, an implication of altered endocytic rate is that it will impact the dynamics of short-term synaptic release properties.
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