Implications for effective treatment of obesity, now second only to tobacco in causing premature death, then involve major behavioral as well as dietary changes.
Since then multipolar mitoses have been identified in a large number of cancers as hallmarks of tumor tissue with direct implications in the causes for aneuploidy (Lingle and Salisbury 1999, 2000; Lingle et al. 1998; Pihan et al. 2003; Pihan and Doxsey 1999; Schatten et al. 1998a, b, 1999a, b, 2000a, b, c; Brinkley and Goepfert 1998; and others; reviewed in Goepfert and Brinkley 2004).
The CIRIA guide said as well as posing a risk, the discovery of unexploded devices can have "significant implications" for builders, causing delays and an increase in costs.
In some of his strongest language on the issue to date, Cable said an in/out referendum had "potentially horrendous" implications, causing "years of uncertainty" for businesses.
Peripheral neuropathy, which usually begins to develop after four cycles of treatment, may have clinical implications; it causes numbness and paraesthesia in a glove- and stocking-like distribution.
These results further show the strength of our approach and suggest interesting implications in the differential regulation caused by both virus genera.
Detailed reviews of IRP structure and regulation have recently been published elsewhere (Refs 2, 3, 4, 5, 6, 7, 8); here, we focus on the role of IRPs in maintaining intracellular iron homeostasis and the pathophysiological implications caused by alterations in this function.
Furthermore, differences in causes could have implications in resource allocation in public health interventions.
At variance with the great majority of protein kinases that become active only in response to specific stimuli and whose implication in tumors is caused by genetic alterations conferring to them unscheduled activity, the highly pleiotropic Ser/Thr-specific protein kinase CK2 is constitutively active even under normal conditions and no gain-of-function CK2 mutants are known.
I offer an articulation of the implications caused by the changing field of research assessment criteria in the United Kingdom that affects the humanities, from a specifically humanities perspective.
