Sentence examples for implications for trials from inspiring English sources

Differences in the proportions of ε4 carriers and noncarriers could also have specific implications for trials of antiamyloid therapies because noncarrier participants may more frequently fail to demonstrate amyloid burden when studied with amyloid imaging [ 51].

These observations, coupled with the efficacy of contemporary medical therapies in reducing clinical event rates, have important implications for trial design of future human in vivo evaluations of vulnerable coronary plaque.

We conclude that almost one out of 20 placebo treated patients discontinued treatment due to AEs, indicating a significant nocebo in trials for depression treatment adversely affecting adherence and efficacy of current treatments in clinical practice, with additional implications for trial designing.

Although effects were not related to a change in outcome (mortality), learning curves in clinical research may have important safety, ethical, research quality and economic implications for trial conduct.

This has important implications for trial design and interpretation, as well as for clinical care.

85 The choice of control interventions has important implications for trial ethics, recruitment, results, and interpretation.

This would have important implications for trial design and interpretation of results.

Our findings also have implications for trial design and patient care.

The related objectives were to explore the nature of any such differences and to examine implications for trial methodology.

The CONSORT PRO extension has important implications for trial design, although design decisions may go beyond simply what should be reported.

It may be that prolonged patient follow-up will be required for such benefits to become apparent; this has resource implications for trial conduct and highlights the potential value of high-quality electronically linked routinely collected outcome data.