From the current study several findings emerged that provide insights into differential effects of rosiglitazone and pioglitazone within the cardiovascular system, including implications for compounding drug efficacy and cardiotoxicity.
This cellular model approach could lead to further studies combining kinase inhibitors with other targeted agents, and suggests possible implications for screening of compound libraries to uncover novel pathway inhibitors.
The implications of this study for compound selection, especially in an academic environment with limited resources, are considered.
This approach has implications for developing novel compounds for structure-based drug design.
The handling and disposal of flowback and produced water also hold implications for air quality because of volatile compounds, such as BTEX compounds, that are often mixed with the fluids.
The results of our study shed light on molecular pathways important in the cellular response of S. cerevisiae to nickel compounds and provide potential implications for further understanding the toxic effects of nickel compounds to human cells.
The results of our study shed light on molecular pathways associated with the cellular response of eukaryotic cells to nickel compounds and provide potential implications for further understanding the toxic effects of nickel compounds to human cells.
Wahyuni, Y., Ballester, A.R., Sudarmonowati, E., Bino, R.J. & Bovy, A.G. Metabolite biodiversity in pepper (Capsicum) fruits of thirty-two diverse accessions: variation in health-related compounds and implications for breeding.
In fact, also those compounds (e.g., fullerene 1) which appear to be well tolerated, according to conventional functional studies, can cause important changes at the transcriptomic level, suggesting potential implications for the toxicity of these compounds.
