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This finding has important clinical implications, demonstrating that the kidney plays an active role in the pathogenesis of type 2 diabetes by excessively reabsorbing glucose and contributing to the maintenance of hyperglycemia rather than to the excretion of the excess filtered glucose load.
In addition these findings have a therapeutic implication, demonstrating that manipulation of this amino acid could increase production of the sAPPα, considered a protective protein, and decrease the generation of toxic fragments such as Aβ40 & 42.
The descriptions of data frequencies in Figures 3 and 4 have a crucial implication, demonstrating significant distinctions between association measures and effect measures [ 9].
Comparative results using two implication operations demonstrate that the proposed reasoning approach performs better.
Relevant to clinical implication, we demonstrate that biweekly intravenous administration of an anti-IgE monoclonal antibody reduces plasma IgE by more than 70% and yields similar suppression of AAAs to those in FcεR1-deficient mice.
There are also the ethical implications – as demonstrated by two recent cases.
The design and optimization implications are demonstrated by using the derived solution to simulate the performance of an immobilized-urease fluidized-bed bioreactor with a recycle loop.
These results have broader implications by demonstrating that strongly felt emotions could be rewarding in themselves in the absence of a physically tangible reward or a specific functional goal.
Human epidemics can have serious health implications, as demonstrated by the most recent outbreaks in Kenya in 1997 and 1998 (5 ) and Saudi Arabia in 2001 (6 ).
In spite of the uncertainties in our analysis, our study provides findings with potential policy implications and demonstrates some important methodological advancements in quantifying the public health benefits of energy efficiency programs.
These findings have theoretical implications in demonstrating that caring is more complex than current models suggest and highlighting the need for models to recognise the non-independence of the positive and negative pathway.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com