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While apoptosis has been widely reported in studies of influenza infection, its implication on disease progression has not been well understood.
To understand the link between tumor immunity and autoimmunity in melanoma and to explore its implication on disease susceptibility and prognosis remains a challenge [ 14].
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She is particularly interested in the distribution of modifiable risk factors (e.g. diet, physical activity, and smoking) and their joint implications on disease burden in the whole population and between demographic subgroups.
The proof of principle of this interaction has broad implications on disease predisposition.
Cluster architecture has implications on disease susceptibility, since cultivars with compact clusters are more susceptible to rot by Botrytis cinerea than those of loose clusters [ 10],[ 13],[ 14].
It further demonstrates that brood removal originally described for honeybees as "hygienic behaviour"–is a widespread sanitary behaviour in ants, which likely has important implications on disease dynamics in social insect colonies.
"Knowing now that the Y chromosome can have effects all over the genome, I think it becomes even more important to look at its implications on diseases," Clark says.
Many new treatment options make unprecedented outcomes achievable in rheumatoid arthritis (RA). 1 2 In parallel, insights on the importance of early effective therapy 3 4 and implications of disease activity on function 5 6 and joint damage 6– 8 led to paradigmatic changes in therapeutic approaches, such as frequent evaluations of disease activity to allow for timely changes of therapies.
Instead of highlighting potentially interesting differences in host acquisition in ticks, the authors focus on implications for disease ecology.
The specific pro- and anti- apoptotic protein signatures revealed in this study could facilitate the understanding of apoptotic and protective immune-mediated mechanisms underlying HIV-1 and HCV co-infection and their implications on liver disease progression in co-infected patients.
However, there is only anecdotal information about variation in transmission rate by age/stage structure in wild animals or the implication of such variation on disease dynamics in zoonotic reservoirs [5] and only limited information in the case of domestic animals (see e.g., [6]).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com