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Future investigation needs to confirm the implication of these genes in urinary bladder cancer.
The expression of these adipogenic genes and those regulators of inflammation correlate positively with VEGF, suggesting the possible implication of these genes in VEGF regulation.
The fact that PTGDS and SASH1 expression remained associated with carotid plaques after adjustment on smoking status may indicate a broader implication of these genes in atherosclerosis than the sole effect induced by smoking.
Further investigations are underway to estimate the implication of these genes in mammalian folliculogenesis.
The possible implication of these genes in heat stress response is discussed.
However, it will be necessary to carry out association and functional studies to demonstrate the implication of these genes in normal pigmentation variation.
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Therefore, we will confirm the clinical implications of these genes in a large cohort of cases.
But the epigenetic implications of these genes in MetS have not been reported.
We further performed pathway enrichment analysis to better understand the biological implications of these genes in the context of the regulatory system.
The implications of these genes, at the CC level, deserve to be addressed in future studies in order to understand their function in follicular growth.
More functional or systemic research studies pertaining to these clustered SelP genes in amphioxus are necessary before a complete understanding of the profound evolutionary implications of these genes can be formed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com