Sentence examples for implication of the er from inspiring English sources
These data confirmed the role of p53 in apoptosis induced by oxidative stress while highlighting a potential implication of the ER in this process.
These data suggest for an implication of the ER in UBB+1-triggered cytotoxicity, but, due to the lack of rescue in the Δ hac1 cells, a critical involvement of the UPR is unlikely.
The implication of "fair er" and "strong er" is that Britain already had these values when it was in the EU.
Knowing the implication of the JNK pathway in ER stress-induced apoptosis, we logically hypothesized that the protection of the Ripk1 −/− cells to tunicamycin-induced apoptosis was a result of defective JNK activation.
However, time-course analysis of ER stress after liver transplantation might lead to a better understanding of the implication of ER stress in liver transplantation before these experimental results are confirmed in a clinical study.
It was interestingly noted that loss of Chop significantly inhibited UUO-induced ER stress as manifested by the reduced expression of Bip, Perk, Ire-1 α and Atf-6, which further supports the implication of CHOP-related ER stress in the development of renal fibrosis.
In conclusion, our study reveals the ability of ER stress to trigger RIPK1 kinase-dependent necroptosis, which opens new doors for future work on the implication of ER stress in pathologies resulting from the inappropriate induction of this inflammatory type of cell death.
An important clinical implication of ER status is the benefit patients derive from endocrine therapies such as tamoxifen.
Following estrogen exposure, a similar increase in both Dnmt3b expression and activit, in endometrial cancer cells was reported and could be inhibited by an ER antagonist, suggesting a direct implication of ER in Dnmts regulation.
