Sentence examples for implication of targeting from inspiring English sources
We have illustrated the implication of targeting hub nodes and proposed network-based drug targets which would cause less side effect.
Although many researchers have reported the clinical implication of targeting CSC surface markers, the fact that the ovarian CSC phenotype was not a consistent state but a changeable state depending on external conditions has been overlooked [ 36].
Regarding the clinical implication of targeting the RAC1 pathway in NSCLC therapy, it has been reported that overexpression of RAC1 is often detected in NSCLC specimens and that there is an association between RAC1 expression with TNM stage and lymph node metastasis of NSCLC.
The Obama administration apparently spent months considering the legal implications of targeting Anwar al-Awlaki, the American citizen who was killed in Yemen last month after being accused of being a terrorist organizer.
In this mini-review, we detail the role of HIF-1α and HIF-2α in intestinal inflammation and injury and therapeutic implications of targeting HIF signaling in IBD.
Finally we discuss the potential therapeutic implications of targeting the functional interaction between ∆F508-CFTR and Dab2.
This review focus on the impact of PTPR alterations across a spectrum of cancers and the clinical implications of targeting PTPRs therein.
We excluded trials focusing on high-risk groups or prevention of psychosis because of the possible ethical implications of targeting interventions at these individuals.
The implication of target organ damage in the appearance of cardiovascular complications, and the possibility of adopting treatments to induce regression of such damage – with improvements in patient prognosis in some cases –, make it necessary to carefully assess silent organ damage.
These findings have potential important therapeutic implications in terms of targeting this signalling axis in human fibrotic lung disease.
These findings have important potential implications for the strategy of targeting ABCG2 as a part of cancer therapy.
