Many studies have indicated an important implication of radiation-induced bystander effects (RIBEs) in cancer radiotherapy, but the detailed signalling remains unclear.
The effects of dose-rate and its implications on radiation biodosimetry methods are not well studied in the context of large-scale radiological scenarios.
This has important implications for minimisation of radiation exposure.
This finding could have profound implications in a field of radiation biology/oncology, in evaluating radiation risk of IR exposures, and for the safety and efficacy of hSC regenerative-based therapies.
If the carcinogenic effect of low dose radiation is greater for the minority of people who are genetically susceptible, this will have important implications for future standards of radiation protection, as well as for liability and compensation.
Such a basic comprehension of the direct effects of radiation may have implications in the design of new chemotherapeutic and radiosensitizing drugs, as well as in the development of more efficient protocols in chemoradiation therapy.
Our findings have important implications for understanding the genetic basis of radiation response, which has remained largely unknown due to the lack of family material needed for genetic studies.
Furthermore, the fact that sperm DNA is damaged by this form of radiation has additional implications for the health and wellbeing of children born to fathers who have experienced high levels of occupational or environmental exposure to RF-EMR around the time of conception.
The implication here is that the very process of radiation and migration on the part of humans was an essential part of the domestication process for rice right from the start.
Further studies are needed to determine accurately the value below which cells tolerate radiation and, more importantly, to uncover the biological implications of low-energy radiation versus low-dose exposure for long-term systems.
Although radiation is predominately considered a "local" treatment modality in that radiation only has direct effects on tumor cells in the field of irradiation, it is clear that the effect of radiation on the immune system has implications for the entire host.
