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In our recent study we demonstrated implication of genetic variation of brain-derived neurotropic factor, modulators of brain plasticity in cognitive processes [15], in pathogenesis of schizophrenia [12].
We further calculated the additive genetic coefficient of variation (CVA) as the square root of divided by the average PDS to assess the implication of genetic variation for adaptive potential (Houle 1992).
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Finally, a brief discussion of the clinical implications of genetic variation is provided.
In this context, to better investigate the implications of genetic variation in the KATP channel, future studies should include ion channel's functional modification due to the SNPs and analysis of SUR subunits.
Unfortunately reference to Fisher's fundamental theorem of natural selection and its implication on genetic variation and its phenotypic expression is missing.
Here, we provide a qualitative discussion of these results, illustrate some implications for the interpretation of patterns of genetic variation in closely related Drosophila species, and suggest that sex specificity is a pervasive feature of interspecific hybridization in plants and animals.
The evidence presented here suggests a possible implication of this cluster in the explanation of genetic variation of production traits.
The ability of a living organism to endure environmental challenges depends on the portion of genetic variation with adaptive implications [ 2] that sustains the formation of ecotypes through ecological evolution [ 3].
This may have interesting implications for the evolution of mating preferences and the maintenance of genetic variation in sexually selected traits.
Because of this, the effect of environmental changes on the expression of genetic variation in the quantitative traits has important evolutionary implications [ 33].
There has been considerable debate about the implications of these findings in the context of larger debates about race and the extent of genetic variation between groups.
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