Sentence examples for implication of alterations from inspiring English sources
Our findings indicate the implication of alterations in NGFR and NGFR genes in schizophrenia, particularly, in defects of synaptic plasticity.
Our findings indicate the implication of alterations in genes encoding NGF and its receptor in pathogenesis of schizophrenia, particularly, in defects of synaptic plasticity detected in this disorder.
At a more integrated level, the implication of alterations of pathways involved in immune/inflammatory activities and coagulation (see Figure 3) is consistent with the known effects of smoking on risk for inflammatory related diseases and stroke [ 1, 15].
Further support for the clinical implication of alterations in the IRE IRP network is provided by the expression of ferroportin – the major or only iron exporter from cells – which can be altered upon loss of its 5′ IRE, as seen in polycythaemic mice (Ref. 92).
Part of our goal is to better understand the functional implications of alterations in individual genomic architectures so that we can make better prediction models.
At present, neither the physiological implications of alterations in the BCAA/AAA ratio nor the effects of systemic inflammation on the cerebral net exchange of LNAAs has been investigated in humans.
In order to elucidate the functional implications of alterations in the miRNA profile it is a widely accepted approach to identify the miRNA target genes by employing specific bioinformatics tools.
Moreover, recent evidence points toward the implication of genetic alterations commonly present in pancreatic cancer, such as those involving p16 or p53, in the 'switching' on of angiogenic phenotypes (Harada et al, 1999; Nishizaki et al, 1999).
This suggestion seems to be in agreement with evidence elicited from recent research, demonstrating the implication of attentional alterations in the pathophysiology of dyslexia, as it is reflected by the N100 component [ 14, 16, 27].
