Sentence examples for implication in diseases of from inspiring English sources

Its possible implication in diseases of modern societies, currently increasing in prevalence, has been reported.

In particular, the interpretation of genetic variants and their implication in disease is one of the major challenges in personalized medicine [ 4- 6].

The results presented demonstrate the modification of the catalytic cysteine of Pin1 by an endogenously produced species that may have potential implications in disease where oxidative stress and deregulation of Pin1 coexist.

The frequency of studied bacteria (Salmonella, Shigella in humans and Salmonella and E. coli) corresponds with the frequency of their implication in diarrheal diseases in the region, their potential for zoonotic transmission to humans and their high rates of resistance to available treatment regimens (Amp, Chl, Cip, Cot, Gen, Kan and Tet).

While its implication in hepatic disease is over-induction of STAT-6, increased collagen, and fibrosis, reduction of normal levels of IL-4 in the corneal environment may tip the balance toward poor stromal keratocyte cell survival, oxidative stress, altered collagen and ECM stability associated with keratoconus [20], [21], [22], [23].

The persistence of high serum NGF levels in intermediate-late forms of SSc strongly suggests of an implication of NGF in disease pathogeny independently of the disease duration.

Although this pattern of pig movements to England highlights the reduced capacity of the Scottish slaughterhouses to process pigs, particular attention should be paid to its implication in the spread of diseases between England and Scotland.

Barrett et al. [ 6] and McGovern et al. [ 8] highlighted ORMDL3 in relation to CD and IBD, respectively, based either on a correlation between genotype and gene expression in lymphoblastoid cell lines [ 7] or on the biological role and previous implication of ORMDL3 in diseases involving dysregulated immune responses.

Because gains at 1q were observed both in low- and high-grade breast tumours, its implication in early stages of disease development has been shown (Tirkkonen et al, 1998; Cummings et al, 2000).

The NLRP3 inflammasome has attracted considerable attention because of its implication in several human diseases and the availability of inhibitors of IL-1 β that have been recently very successful in clinical trials with patients suffering from gout and type 2 diabetes.

This has led to its implication in a range of autoimmune diseases affecting the gastrointestinal tract [ 12], such as inflammatory bowel disease [ 13], colorectal cancer [ 4], type 1 diabetes [ 5] and metabolic syndromes [ 14].