The initial findings that elevated PERP expression resulted in increased p53 protein levels in MEL202 cells suggested a role for PERP in the positive feedback regulation of its own transcriptional regulator, with potential implications for the regulation of p53 and the vast array of p53-targets involved in the tight control of cell cycle arrest and apoptosis.
Some implications for the regulation of insolvency procedures are discussed in Sect.
The multiple subunit structure of the spliceosome has implications for the regulation of a splicing event and for its possible catalysis by ribozyme or ribozymes.
While it is has long been appreciated that cellular glutathione homeostasis is regulated by factors such as synthesis, degradation, transport, and redox turnover, relatively little attention has been paid to the influence of the intracellular partitioning on glutathione and its implications for the regulation of cell functions and signalling.
These findings have implications for the regulation of ILK kinase activity in vivo.
This work has important implications for the regulation of cytoplasmic dynein in neurons and will allow additional experiments to further probe the mechanisms of neuronal dynein regulation.
The identification of splice variants associated with the free living, interaction, and mycorrhizal states may have implications for the regulation of metabolic, functional, and metabolic capabilities.
The formation of this dimer would therefore block the recruitment of tyrosine phosphatases and may have important implications for the regulation of Src kinase activity.
The dimerization of Csk could therefore have a profound influence on the recruitment of phosphatases to sites of Src kinase activity, with important implications for the regulation of the Src kinases.
Indeed, the organization and structure of the genome has potentially important implications for the regulation of transcription and the possible interpretation of the naturally occurring genetic variation in humans [24].
Further studies based on these findings are required to assess the implications for the regulation of cellular responses of ERK1 complexation with histones and VDAC in the mitochondrial compartment.
