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Furthermore, no measurable progeny were recovered from a host carrying a deletion in the PolI 5′→3′ exonuclease domain [ 7], clearly implicating the essential requirement of an active FEN for viral replication.
Furthermore, members of the redox protein family, such as thioredoxin-1, have been reported to exert a positive effect on HIF-1α expression, 34, 35 implicating the essential role of redox protein in HIF-1α upregulation.
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These novel findings therefore implicate the essential involvement of the β1-integrin SSH1 Cofilin pathway in mitochondrial and synaptic dysfunction in AD.
Although initial studies implicated the TPR domain as essential for interaction with both Hsp90 and Skp1 (Bansal et al, 2004), further analysis suggests that the N-terminal TPR domain mediates interactions with Skp1, whereas the central CS domain is responsible for the recruitment of Sgt1 to Hsp90 (Lee et al, 2004; Lingelbach and Kaplan, 2004; Catlett and Kaplan, 2006).
The treaty says that Hong Kong can refuse to transfer a suspected criminal to the United States if giving up the person "implicates" the "defense, foreign affairs or essential public interest or policy" of the People's Republic of China.
For example, Hong Kong has the right to refuse to turn over a person when surrender implicates the "defense, foreign affairs or essential public interest or policy" of the PRC.
Hypoxia implicates the actin cytoskeleton through its essential roles in motility, invasion and proliferation.
This variable penetrance probably reflects differences in the genetic backgrounds of the mice analyzed and also implicates BMP4 as the essential activator of lens induction.
This phenotype observed in TBI mice is reproduced in uninjured mice that have been infused with purified BDMPs, implicating an essential role of MPs in the development of coagulopathy.
Recently, a large body of evidence has shown that vesicle trafficking and exocytosis are essential in tumorigenesis, which implicates the Rab family proteins [ 11– 13].
It has been also conceptualized as a whole systems change implicating essential actions in many systems, including the sociocultural, and educational systems as well as the system pertaining to the profession itself 1 [ 6], through which a health professional role (namely the midwife's role) evolves.
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