Sentence examples for implicating interactions from inspiring English sources

Moreover, results implicating interactions between the N-term and ICL4 segments in the inward-opening isomerization of the hDAT construct are consonant with experimental studies in the GABA transporter (GAT1) in which the same two regions have been shown to modulate forward as well as reverse substrate transport.

A series of reports by another group using full-length purified UNG2 have implicated interactions of the N-terminus with the active site [29] [31].

Indeed, both epidemiological evidence as well as in vitro data exist to implicate interactions of HPV and cigarette smoke carcinogens in the progression of cervical cancer [ 26, 27, 68].

Using this strategy, previous interaction studies in LOAD (e.g., [ 20– 24]) implicated interactions between CR1 and APOE using quantified A β PET as the outcome variable [ 24] and between cholesterol trafficking genes [ 21, 22] and tau phosphorylation genes [ 20] in case-control analyses.

However, the interaction was also significantly reduced in high ionic strength buffers (≥300mM; p<0.01 one-way ANOVA analysis relative to125mM NaCl), consistent with a physiologically relevant interaction and implicating electrostatic interactions in the seeded formation of PrPres.

Addition of the recombinant 4-1BB-Fc but not control-Fc protein efficiently prevented up-regulation of T lymphocyte proliferation by HDACi-stimulated Raji cells, implicating 4-1BB/4-1BBL 4-1BB/4-1BBL 4-1BB/4-1BBLased prolinteractionsin. 6C).

Thus, although binding to the IVS1-6A allele was reduced in vitro, U2AF65 acted antagonistically to PTB and PUF60 in vivo, implicating additional interactions.

Mnt:Max, Myc Max, and Mondo:Mlx heterodimers have been verified in both vertebrates and Drosophila, implicating their interactions are ancestral.

For example, our model integrated information from physical mapping (based on chemical cross linkers), from structural information reported in the literature, from our findings implicating KBU2046 interaction with HSP90/CDC37 heterocomplexes, and only took into consideration heterocomplex structure (i.e., in the absence of bound client proteins).

Studies implicating the interaction of Vir components in A. tumefaciens as well as several other bacteria are rapidly growing and, coupled with recent structural studies, the architecture of the Vir scaffold is coming to light (Figure 1B).

When HIV-1 virus-like-particles (VLPs) are produced in the presence of TRIM5αrh, TRIM5αrh is efficiently incorporated into VLPs, implicating the interaction between cellular and viral components during viral assembly [16].