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Initially, diminished HDAC1 and HDAC2 expression and a reduced total HDAC activity were described in synovial tissues of RA compared with OA patients, implicating a shift towards histone hyperacetylation in patients with RA and pointing to a potential role of HDACs in the pathogenesis of RA [ 36].
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One transition involves a change in the correlations dimension by 1937, while a second transition implicates a shift in the short-scale Hurst exponent by 1945-1946.
These examples implicate a shift to personalized ESA administration with more frequent, but lesser doses.
This activation-related conformational switch also implicated a shift in exosite binding affinities of the gelatinases.
The classification according to the St Gallen molecular subtypes in primary tumours and matched lymph node metastases, implicates a shift to a more aggressive subtype in synchronous lymph node metastases compared to the primary breast tumour.
The majority of these operons encode proteins whose functions have not been determined yet, implicating a significant function shift.
This implicates a unique shift of "host" (mobilizing factor) during the evolution and divergence of ta-TRIMs in taeniids.
EIT measurements at a juxta-diaphragmatic level implicate a potential shift of morphologic structures into the EIT sensitivity region affecting data interpretation.
We concluded the msn lamellocyte enhancer AP-1 sequence could compete for dFos/dJun binding in this electromobility shift competition assay, again implicating a role for the AP-1 complex in the positive regulation of enhancer activity.
Thus, our results provide evidence of early splenocyte apoptosis triggered by HS, implicating an initial pro-apoptotic shift, counter-regulation, and subsequent rebound effect.
Furthermore we show that aggressive MCL implicates a gene network shift to higher expressed genes in late cell cycle states and refine the set of non-proliferative genes implicated with bad prognosis in MCL.
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CEO of Professional Science Editing for Scientists @ prosciediting.com