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While we do not purport to know the molecular mechanisms by which amiodarone HCL leads to the toxicity we observed in NSCs, it is notable that the results of our automated screening, including GSEA and microarray analysis, are all consistent with published literature that implicates the roles of ion channels and TNFα signaling in amiodarone-mediated cytotoxicity.
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This implicates the role of H-bonding network in binding of quinone/semiquinone and defining thermodynamic properties of Q/SQ/QH2 triad.
In addition, the discovery of substantial nickel deposits in China that have been dated to that time implicates the role of Methanosarcina in the Permian extinction.
Although accumulating evidence implicates the role of dorsolateral prefrontal cortex (dlPFC) in complex value-based learning and decision-making, direct evidence for involvements of this region in integrating information across sequential decision states is still scarce.
This implicates the role of climate as a primary preconditioning factor for slope failures in this highly active tectonic region.
Statements of opinion imply something about how the belief was formed, and that process implicates the role of directors as fiduciaries.
Although much evidence implicates the role of the amygdala in anxiety [6], [7], little data is available regarding the neuronal correlates of anxiety in the amygdala.
This difference implicates the role of the octyl side chains in driving molecular organization in the solid-state.
A growing body of direct evidence implicates the role miRNAs in T2D and most of its pathophysiological aspects.
Residual variation is individual specific and heritable as quantitative trait, which implicates the role of transacting factors as modifiers of somatic instability [ 88].
The independent link between Epworth score and MS in patients with OSA implicates the role of daytime sleepiness and chronic hypoxia as a potential mediator.
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CEO of Professional Science Editing for Scientists @ prosciediting.com