Gene expression and protein array data implicate several factors that help to explain the molecular basis underlying the unique architecture of vascular channels formed by aggressive breast cancer cells and regulated by COX-2.
Studies from a variety of model systems have implicated several factors, including the Paf1 complex, the chromatin remodeler Chd1, the histone modifying complex NuA3, and the Drosophila HP1 protein as being at least in some cases responsible for the recruitment of FACT to sites of active transcription (Duina 2011).
Our analysis of the genes encoding proteins whose abundance is cell cycle-regulated implicates several transcription factors as being particularly important for the control of protein expression during the cell cycle.
Studies examining barriers to timely and adequate prenatal care have implicated several contributing factors, including unwanted or unplanned pregnancies, reduced access to primary care, and no education beyond high school [18] [21].
It is likely that many of these confounding variables, including ancestral genetic background, may influence the oocyte pool, follicular atresia, and reproductive lifespan, implicating several causative factors in differences between racial groups.
Recent studies have implicated several risk factors for ESBL-E colonization at admission: prior ESBL-E carriage, transfer from hospitalization units and especially long-term care facilities or ICUs, coming from a high-prevalence country, poor functional status, current antibiotic use and chronic renal insufficiency [ 14, 17, 19- 23].
Investigations into the mechanisms in cells that regulate sensitivity to TRAIL have implicated several pathways and factors.
The WQS analysis also implicated several chemicals as NHL risk factors that were not associated with NHL when evaluated individually.
In contrast to most pediatric cancers, there is a growing body of literature in the United States and internationally that has implicated several environmental, infectious, and dietary risk factors in the etiology of childhood leukemia, mainly for acute lymphoblastic leukemia, the most common subtype.
It implicated several Soviet spies.
