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The analysis presented here implicates over-expression of Myc, Akt, c-Src, or erbB-2/HER2 with activation of their associated pathways in at least a subset of prostate tumors.
Several studies also implicate over-expression of IGF2 in colon cancer and in ovarian cancer [ 15].
Other studies are implicating over- or underexpression of genes known to be involved in the body's circadian clock.
Another GWAS has implicated over-expression of the gene that codes for thymic stromal lymphopoietin (TSLP) as an important factor in disease development.
It was not clear if this was an effect of EphB4 on metastasis or a result of accelerated tumour growth but these results clearly implicate over-expression of EphB4 in tumour growth and/or establishment of the invasive phenotype in the adult mammary tumours.
TDAG8 is transcriptionally up-regulated by glucocorticoids (GCs) and implicated by over-expression studies in psychosine-mediated inhibition of cytokinesis [18], [19].
New details of the lavish lifestyles and alleged crimes of those implicated over the years are splashed almost daily over the front pages of Brazil's newspapers.
That came after a number of the sports' biggest stars were implicated over the last year in the federal investigation of the Bay Area Laboratory Co-Operative, or Balco.
Al-Liby - real name Nazih al-Ragye - has been implicated over the 1998 bombings of the US embassies in Kenya and Tanzania that killed 224 civilians.
The US secret service faced further damage on Friday when it emerged that three more agents are to leave and a twelfth employee has been implicated over the Colombia prostitution scandal.
This includes a report involving 150,000 individuals with over 35,000 schizophrenic patients that has implicated over 108 genetic loci [16].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com