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Structural and phylogenic evidence implicates a single causative amino acid replacement at the same SP1 position along both lineages.
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The study is the first to implicate a single genetic pathway in the development of both the forebrain and the face, and it may provide insights into some birth defects.
The findings of our study implicate a single gene cluster as encoding the MtaR-controlled methionine transport system.
Thus, rare variant association signals are observed in two different varieties, either by implicating a single variant or by implicating an entire gene.
Phylogenetic analyses implicate a single Ty3/gypsy-like sublineage (sublineage E') as a candidate proliferative source lineage of Ty3/gypsy-like retrotransposon amplification in the hybrid species.
Linkage analysis implicated a single region of approximately 6 cM between markers D16S419 and D16S3032 at a logarithm of the odds (LOD) score >1.5.
For other regions we tested orthologs of multiple human genes, and at six of the remaining regions our sucrose toxicity screen implicated a single human gene ortholog.
Somewhat contrary to expectations, our results did not implicate a single species of animal as being the sylvan source of MPXV for the U.S. outbreak.
Limitations of this report include the lack of neuropathologic confirmation and insufficient information to strongly implicate a single commercial cadaveric hGH product as infection source.
Chromosome complementation studies, where all or part of a chromosome is introduced into cell lines with LOH of that chromosome via microcell-mediated monochromosome transfer, have frequently been able to show reduction in tumorigenicity of the cell line thus complemented [ 23, 24], but have only rarely been able to implicate a single gene responsible [ 25, 26].
Research has implicated a single-celled protozoan, but other factors may be involved.
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CEO of Professional Science Editing for Scientists @ prosciediting.com