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Our study implicates a distinct signaling pathway whereby FGF-2 acts to block Smad-mediated fibroblast activation through a MEK-ERK-dependent mechanism in valvular interstitial cells.
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On the other hand, relatively poor performance for the natural and the synthesized voice compared to the nonvocal timbres would implicate a distinct status for processing voices.
Two factors may be implicated: (a) distinct deficits underlying the antisocial conduct of CD subgroups, (b) plausible disjunction between cognitive and affective perspective-taking with subgroups presenting either cognitive or affective-specific deficits.
2) That these 'extra' homologs form a loose group of atypical FabB/F's with other sequences from R. baltica, a non-anammox planctomycete, and a number of deltaproteobacteria. 3) That some of these homologs from the two planctomycetes (and one of the deltas) do not contain many of the canonical conserved active site residues, strongly implicating a distinct function.
However, his statement implicates a broader meaning.
The rapid onset implicates a neural mechanism.
Furthermore, modifications to amino acids (e.g., phosphorylation) implicate a protein in distinct and often transient biological processes (e.g. regulation of gene expression).
Different DM1 allele size distribution between blood and male germline implicates the distinct mutational dynamics in these tissues.
Custom-designed, high-resolution microarray analysis of additional ACD/MPV samples revealed one microdeletion harboring FOXF1 and two distinct microdeletions upstream of FOXF1, implicating a position effect.
While these results implicate a role for NF2 in regulating Hippo signaling in two distinct tissues, additional work has demonstrated a similar anti-proliferative but non-Hippo-related effect.
Hence, these previous observations concerning p38 and Akt isoforms, coupled to the current ones with regards to PI3-K isoforms and isoform complexes, further underlie the undeniable fact that the regulation of cell survival and anoikis constitutes a highly complex issue that implicates distinct mechanisms according to the cell type at the very least [ 3– 6, 9, 10].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com