Exact(1)
Subsequently, we experimentally validated a subset of computationally inferred patterns of overlapping AS patterns, by RT-PCR and direct sequencing, analyzed implicated sequence and transcript features, and compared A5Es with constitutive and pseudo-exons, as well as A3Es, in H. sapiens and M. musculus.
Similar(59)
Glycosidic linkage and pyranose ring flexing were affected by branching, linkage position, and secondary structure, implicating sequence dependent motions in glycomic functional diversity.
So far, evidence for most mRNAs implicates sequences in the 3'-untranslated regions in control of mRNA decay and translation [ 13, 14].
P. falciparum apPOL, the first structural representative of a plastidic A-family polymerase, diverges from typical A-family members in two of three previously identified signature motifs and in a region not implicated by sequence.
In this study, time-dependent BOLD activity changes in the region of interest implicated a sequence of cortical gray matter blood flow changes beginning with hyperemia, followed by hypoperfusion with attenuated response to visual activation and subsequent return of resting blood flow to baseline with recovery of stimulus driven activation [ 89].
Previous work has implicated two sequences in nephronectin, RGD and DLFEIFEIER, that interact with the α8β1 receptor, but characterization of the active ligands and their binding to the integrin remain incomplete.
No identifiable genes were found, but one cDNA sequence (GenBank accession EF443049) was represented in one mtDNA clone, implicating this sequence as an additional transcriptional unit of the mitochondrial genome.
A high frequency of somatic mtDNA mutations has been reported in various adult post-mitotic cells and in cancer tissues, implicating mtDNA sequence variation in physiological aging and tumorigenesis [2], [4], [6] [13].
We are not aware of any data implicating polypyrimidine sequence in nucleosome positioning, although related poly-T tracts have recently been found to demarcate gene transcription start sites in the AT-rich genome of Dictyostelium discoideum (Chang et al. 2012).
These results imply that distal CRMs do not affect the noise mean expression relationship and are consistent with studies in yeast implicating promoter sequence and nucleosome occupancy at the transcriptional start site in expression noise control (Tirosh and Barkai 2008; Hornung et al. 2012; Carey et al. 2013).
GM, AC, BSand SSwere implicated in BAC clone sequencing, sequence assembly and verification of assembled sequences.
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