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Moreover, the assessment of functionally implicated response predictors in these clinical trials may help to identify the patient subgroup most likely to benefit from treatment with dasatinib.
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In this last class, genes implicated in "Response to radiation" (GO 0009314) and "Response to wounding" (GO 0009611) were identified.
This region was identified through the BOLD response t-test and was chosen because right inferior gyrus is highly implicated in response inhibition.
PNPs are also implicated in response to abiotic stresses (e.g. phosphate deprivation [ 11]) as well as in response to plant pathogens [ 12].
The scans revealed that responding to a cue and inhibiting a response produced overlapping activation patterns in brain regions within the right frontal and parietal lobes, a network that has previously been implicated in response inhibition.
The LEA proteins, including the LEA 3 family, have been implicated in response to water stress, though the exact function of these proteins is not clear [38] [41].
Because certain gene mutations may be implicated in response to these agents, we also checked the mutational status of BRAF, KRAS, EGFR and PI3K in these cell lines.
MYB is implicated in response to development and metabolism [ 67].
The right inferior frontal gyrus has been implicated in response inhibition [ 15].
miRNAs has been implicated in response to DNA damage and repair.
Both TP53 and KRAS mutation have been implicated in response of patients to therapy.
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