Sentence examples for implicated loss from inspiring English sources

Early karyotype/phenotype correlations studies implicated loss of the short arm in growth failure.

However, a number of observations have implicated loss of ARE-mediated post-transcriptional regulation in the neoplastic transformation of cells [ 11].

While epithelial malignancy is not a common feature of TSC, studies in this laboratory and others have implicated loss of function of TSC1 in bladder tumorigenesis (17– 17).

Copy number analyses have implicated loss of heterozygosity of chromosomal regions 9p, 17p and 21q in the potential development of these tumors [ 17].

This study clearly implicated loss of E-cadherin as a second and collaborating hit in tumor formation and provided a compelling example of how genetic and environmental factors cooperate in the initiation of distinct tumors.

BP mapping implicated loss of function of SATB2 as the cause of the clinical phenotype (10) with the transcription unit being directly disrupted in one case and the BP located 130 kb 3′ of the polyadenylation site within a large gene desert in the other.

Absence of the IIH6 epitope implicates loss of the ligand interaction site on dystroglycan.

Hence, preclinical studies strongly implicate loss of MMR, in particular loss of hMLH1, in overcoming apoptosis by cisplatin.

Current evidence implicates loss of intervertebral disc (IVD) matrix consequent upon disc 'degeneration' as a major cause of low back pain [ 1].

25, 24, 27 While the exact functionality of G130V is unclear, the present data implicate loss of protein for its pathogenicity.

Chromosome 8p is frequently lost in CRC, many studies implicate loss in later stage disease and metastases [ 13- 15], and several 8p genes have been implicated in metastasis [ 16- 19].