Sentence examples for implicated in the repair of from inspiring English sources

To determine whether the conservative HR is also implicated in the repair of Top2-mediated damage, we analyzed several end points.

The work reported here was designed to set the record straight with respect to the effects of the genes significantly implicated in the repair of EcoKI breaks and in particular to investigate the pathways of resolving recombination intermediates.

Some of these proteins were also shown to be implicated in the repair of membrane tears of muscle fibres like annexins which are fusogenic proteins with affinity for membrane lipids and phosphoinositides [14], [29] or MG53, a protein implicated in vesicular trafficking [12].

Several helicases have been implicated in the repair of stalled replication forks [1,7].

The product of this gene has been implicated in the repair of damaged Fe-S clusters, and its expression is stimulated by iron starvation (35, 54).

Nucleotide excision repair (NER), mismatch repair (MMR), and base excision repair (BER) have been implicated in the repair of ROS-induced lesions in DNA.

Cytokines, such as ANGPT1 and VEGFA, have been implicated in the angiogenic/haematopoietic repair of the murine bone marrow endothelium following pre-conditioning prior to transplantation in vivo (Kopp et al, 2005; Hooper et al, 2009).

Bcl-2 has been implicated in the negative regulation of repair of various types of DNA damage in the nucleus [ 7, 28, 29, 44].

We observed, for instance, a higher number of substitutions in methylated CpG sequences, implicating MMR in the repair of methylated cytosine deamination and demonstrating that MMR disconnected from the replication fork is also critical to maintain genomic integrity.

BMPs 7, 12, 13 and 14 have been implicated in the neoformation and repair of tendons [8], [15], and of these, BMP-12, the human homologue of mouse growth and differentiation factor 7 (GDF-7), has been shown to promote tendon differentiation and formation both in vivo [16] and in vitro [7], [17].

This combined effect of XPC and XPD polymorphisms could support the hypothesis for this population that changes in genes implicated in the NER repair pathway contribute to the susceptibility of developing lung cancer, and the combination of genotypes with a reduced ability to repair DNA lesions could result in a higher risk of developing this disease.