A group of maternal SET domain genes, which are implicated in the programming of histone modification states in early development, have been identified and predicted to be responsible for all known sites of SET domain-mediated histone methylation.
For instance, epigenetic mechanisms have been implicated in the programming of cell fate and differentiation [43] [50], in defining ultimate activity levels of specific functional systems [22], [24], and in mediating environmental modulation of genetically-based developmental programs [22], [24], [42], [51], [52].
In other words, contrary to the plotline of "Zero Dark Thirty," and contrary to self-serving accounts of C.I.A. officers implicated in the interrogation program, senators with access to the record say that torture did not produce the leads that led to finding and killing bin Laden.
Furthermore, the RAS has been implicated in the developmental programming of hypertension in sheep and rodent offspring exposed to glucocorticoids in utero (58 – 60).
Finally, we manually integrated the TNFα network with the connections to all major factors the network analysis had implicated in the NKX3.1 transcriptional program, including FOS/AP1, MYC, and p53.
Sanders told Couric another reason he opposes the bill is because he feels "corporate America" is equally implicated in the widespread data collection programs.
RORγt is a pivotal regulator of a pro-inflammatory gene expression program implicated in the pathology of several major human immune-mediated diseases.
The transcription factor SCL and its binding partners are implicated in the induction of the hematopoietic program in mesoderm and the generation of hemogenic endothelium (Gering et al., 2003; Lancrin et al., 2009).
More recently, we have demonstrated that transient proteasome inhibition from 1 to 9 hpi allows fertilized oocytes to delay the onset of zygotic gene activation, indicating that proteasomal degradation of maternal proteins is implicated in the establishment of the embryonic program during the MZT (Shin et al., 2010).
There are so many programs implicated in the sequester that it would take months, and a team of data scientists, to answer that question.
