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However, despite RECQL5 being phenotypically implicated in the preservation of genome integrity at several levels, the mechanistic basis for its function remains poorly understood.
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In addition, as miR203 targets ΔNp63 α and BMI1, another protein implicated in the preservation and activity of stem cells, it will be of interest to determine if miR203 expression can identify patients at low risk for breast cancer recurrence.
The exacerbated response of the KO aortic endothelium to HFD suggests a greater derangement of metabolic signaling in these cells and implicates LGALS3 in the preservation of such pathways.
None of these genes/proteins was previously cited as being implicated in the DNA-preservation or the DNA-repair machineries.
Attenuated activity of the insulin/IGF-1/PI3K pathway has been implicated in the development of metabolic diseases such as type-2 diabetes, and preservation of the activity of this signalling pathway is thought to be essential for glucose and lipid homeostasis in the long term (Engelman et al, 2006).
How is accounting implicated in the ordering of public space?
Stephen Clark was thus implicated in the deaths of both Christopher and Harry Clark.
(A related area was implicated in the processing of jokes).
And he is implicated in the death of John Smith.
Additionally, PrPC might be implicated in the pathogenesis of AD.
Oxidative stress has been implicated in the pathogenesis of NAFLD.
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