Moreover, we found that the p38 MAPK was implicated in the post-transcriptional regulation of IL-8 following TLR3 activation.
Itch is a member of the HECT domain-containing E3 Ub ligases and has been implicated in the post-translational modification with Ub of CXCR4, followed by desensitization at the cell surface by engagement to its cognate ligand SDF-1α [70].
Such rapid changes in genomes have been implicated in the post-zygotic isolation of several Drosophila species demonstrating the critical role of satDNA in hybrid incompatibility.
LV remodeling is directly implicated in the post-infarction development of ventricular dilatation, a predictive sign for a future HF [ 8].
Regulation by ERs has been implicated in the post-transcriptional regulation of c- myb gene expression [ 4] and the c- myb gene is involved in recurrent translocations in some breast tumors that are positive for expression of ERs [ 5].
We have currently observed that the testicular expression of MIWI, an RNA-binding protein, implicated in the post-transcriptional inhibition of protein translation, is downregulated in the testes of CPA-treated rats.
Recently, two additional factors, rfs-1 and helq-1, have been implicated in the post-invasion steps of HR and, as predicted, interact genetically with rtel-1 (Ward et al. 2010).
We thus propose that the 3'UTR of Hes5-1 implicatedted in the post-transcriptional regulation of its mRNA, and this sequence was included in the pHes5-VNP Notch reporter to allow it to better reflect Notch activity.
Mutants defective in function of TldD or TldE (also called PmbA) accumulated the precursor of the antibiotic [ 16, 17], and the encoded proteins were also implicated in the post-segregational killing by the F plasmid, which comprises two cognate factors, a stable toxin CcdB and a labile antitoxin CcdA.
These results strongly suggest that only ATM and DNA-PK activities are implicated in the H2AX post-translational regulation.
It is required for both the establishment and maintenance of Golgi structural integrity, it coordinates passage of cargo through the Golgi, and it is implicated in the accurate post-translational processing of plasma membrane proteins.
