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The scans revealed that responding to a cue and inhibiting a response produced overlapping activation patterns in brain regions within the right frontal and parietal lobes, a network that has previously been implicated in response inhibition.
This region was identified through the BOLD response t-test and was chosen because right inferior gyrus is highly implicated in response inhibition.
This work has already identified several metabolites and genes implicated in response to escitalopram, followed by functional validation, demonstrating how joining multiple "omics" creates novel insight into mechanisms of variation of response to treatment with antidepressants.
Because certain gene mutations may be implicated in response to these agents, we also checked the mutational status of BRAF, KRAS, EGFR and PI3K in these cell lines.
The LEA proteins, including the LEA 3 family, have been implicated in response to water stress, though the exact function of these proteins is not clear [38] [41].
In Arabidopsis, DREB1A gene and its two homologs are implicated in response to low-temperature stress, in a manner independent of ABA, and its transcripts peak during the presumptive day, whereas expression of the DREB2A gene and its single homolog was induced by dehydration [47], [58].
Similar(30)
Components of several regulatory systems have been implicated in responses to ROS.
Three cysteines and a lysine in the N-terminal region have been implicated in responses to reactive chemicals [26] [27].
Proline is probably the most widely distributed osmolyte in plants [15] and is implicated in responses to various environmental stresses [14].
In stems, the LM13 epitope is mostly abundant in epidermal walls and implicated in responses to mechanical stress [ 29, 30].
GFI1 is involved in diverse developmental processes but has not previously been implicated in responses to tobacco smoke.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com