Sentence examples for implicated in reduced from inspiring English sources

This is of particular importance since expression of MDR-1 and its encoding protein P-gp have been implicated in reduced drug up-take, thereby mediating resistance to chemotherapy [ 36, 37].

We observed deterioration of trabecular architecture, decreased bone mass, and decreased cortical thickness, all of which have been implicated in reduced bone strength and increased fracture incidence in humans (Barth et al. 1992; Wachter et al. 2002).

Poulsen, M. et al. Methylotrophic methanogenic Thermoplasmata implicated in reduced methane emissions from bovine rumen.

The p53Ser220 mutation has been implicated in reduced efficacy and drug resistance in the context of osteosarcomas and breast tumors treated with doxorubicin-based protocols.

Lead is implicated in reduced somatic growth [12], decreased brain volume [5], spontaneous abortion [13], nephropathy [14], cancer, and cardiovascular disease [15], [16].

Vitamin D deficiency is implicated in reduced serum albumin concentrations [ 29].

Dietary substances such as vitamin B, caffeine, and alcohol also have been implicated in reducing the risk of Alzheimer disease.

This zone contains the superficial protein (SZP), a proteoglycan synthesized exclusively by superficial zone chondrocytes and implicated in reducing the friction coefficient of cartilage.

Similarly, DinJ, the toxin component of the dinJ/yafQ TA module, has been implicated in reducing σ38 levels through directly repressing the transcription of cspE, which in turn positively affects σ38 translation through stabilisation of rpoS mRNA20.

Molecular pathologic mechanisms implicated in reducing nephron endowment are multifactorial: Poor antenatal perfusion with lack of oxygen and nutrition, in particular protein and micronutrients at a time-critical window for the developing kidney impact nephron numbers [16].

While Y4 agonism with PP in the brainstem is implicated in reducing food intake via indirect effects on gastrointestinal function, the hypothalamus also appears to be involved.