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None were implicated in providing false-positive results on any DOA screen.
Similarly, certain dental restorative resinous materials have been implicated in providing saline-extractable components that were toxic to human gingival fibroblast cells (HGFCs), but the identities of these extractable substances have not been revealed by analysis.
These posterior parietal brain regions have been implicated in providing awareness of the body's position and location in space, notes Richard Davidson, a neuroscientist at the University of Wisconsin, Madison.
For instance, a study at the University of Birmingham in the UK has uncovered that "prior to fertilization, a cloud of cumulus cells surrounding the egg releases progesterone, the female sex hormone, triggering a calcium influx into the sperm... Progesterone has also been implicated in providing a chemical gradient by which sperm can navigate toward the egg".
Astrocytes, the major non-neuronal cells in the brain, have been implicated in providing tropic support for the neurons.
These acidic residues are implicated in providing selectivity towards cationic amphipathic drug molecules through ionic interactions during their entry into the drug binding site of ABCB1.
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Astrocytes have also been implicated in both providing useful factors for remyelination and impeding it, with astrocytic scarring [ 55].
Interestingly, canonical Wnt signaling has also been implicated in fibrosis, providing a molecular link between fibrosis and angiogenesis (Bowley et al., 2007).
Recent studies have proposed TCTP as an androgen-regulated gene implicated in PC, providing preclinical proof-of-principle that combining antisense oligonucleotide-mediated TCTP knockdown with castration and/or docetaxel therapy could serve as a novel strategy to treat CRPC [ 9, 19].
Having defined aberrant genomic regions in two breeds of dog with a high incidence of HS, subsequent comparative molecular analysis of such regions, both in dog and human patients, will provide opportunities to gain greater insight into our understanding of the pathways implicated in histiocytic cancers, providing a first step on the road to developing new treatments.
APOE is implicated in psoriasis by providing protection against some infections, as well as by modulating mitogen-activated T lymphocyte proliferation [ 33– 33].
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