Polyamines (putrescine, spermidine and spermine) are small aliphatic molecules implicated in a myriad of cellular processes, including DNA condensation, replication, RNA transcription, translation, ion channel function, embryonic development, angiogenesis, and apoptosis5,6,7,8,9,10.
Vitamin D is not only a key component in the maintenance of calcium homeostasis and bone health, but has also been implicated in a myriad of other non-skeletal biologic systems.
Ubiquitination resulting in both degradative and non-degradative forms of protein regulation have been implicated in a myriad of cellular processes.
In addition to refilling stores, SOCE has been implicated in a myriad of diverse processes, including gene expression, apoptosis, and exocytosis (review by[6]).
ATM and ATR are kinases implicated in a myriad of DNA-damage responses.
Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related (ATR) are kinases implicated in a myriad of DNA damage responses [ 1].
CNVs have been implicated in a myriad of diseases, including autism and schizophrenia, where CNV identifications have pointed to new gene loci of disease [ 97].
Because miRNAs have been implicated in a myriad of biological functions and disease processes, it is not surprising that their biogenesis is regulated at many levels.
1, 2 In recent years, HDACs have received increasing attention in the context of neurological disease not only because protein acetylation has been implicated in neuropathology in myriad ways but also because HDACs are druggable targets.
JUN encodes a subunit of the AP-1 transcription factor implicated in response to a myriad of physiological and pathological stimuli (reviewed in Hess et al., 2004).
