Exact(5)
Even though oncogenic Met signaling remains the major research focus, the HGF Met axis has also been implicated in infectious diseases.
Abiotrophia adiacens has been implicated in infectious crystalline keratopathy, endophthalmitis, and neonatal conjunctivitis [7].
The single immunoglobulin and IL-1 receptor (SIGIRR), found up-regulated in our patients 1.55 fold, is implicated in infectious and sterile inflammation, as well as autoimmune disease.
Nineteen biomarkers were selected because they represent markers of novel pathways implicated in infectious disease pathobiology, including inflammation, coagulation, and endothelial activation [ 19- 26].
The deregulation of TNF- α production has been implicated in infectious disease [ 27– 29] and in a variety of human diseases including cancer [ 30– 32], Alzheimer's disease [ 33], major depression [ 34], and inflammatory bowel disease [ 35].
Similar(55)
In addition, it has also been implicated in some infectious diseases.
Permeability barriers for and active efflux of drug molecules are two resistance mechanisms that have been implicated in various infectious outbreaks of antibiotic-resistant pathogens, suggesting that these mechanisms may be good targets for new drugs.
This phenomenon may explain the persistence of P. gingivalis implicated in chronic infectious and inflammatory lesions [9].
Human T-cell lymphotropic virus type 1 (HTLV-1), the causative agent of adult T-cell leukemia/lymphoma (ATLL) [1] and of tropical spastic paraparesis/HTLV-1-associated myelopathy (TSP/HAM) [2], has also been implicated in pediatric infectious dermatitis [3], uveitis [4], arthropathy [5] and polymyositis [6].
Enolase has been implicated in many infectious, autoimmune, and inflammatory diseases [ 10, 22- 24].
S100A8 and S100A9, generally functioning as the S100A8/A9 heterocomplex, and S100A12 are implicated in non-infectious chronic inflammatory diseases such as RA, psoriasis and inflammatory bowel disease [ 21- 25].
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