Sentence examples for implicated in frequent from inspiring English sources

In t-AML a 40kb deleted MCR pointed to RUNX1 on 21q22, a gene coding for a transcription factor implicated in frequent rearrangements in leukemia and in familial thrombocytopenia.

Somewhat surprisingly, analysis of such subunit families significantly enriched at the boundaries of duplications (arrows in Figure 2B) revealed that 46% of the subunits implicated in frequent past duplication events harbored or were adjacent to Alu elements.

One of the main goals of our study is to identify and characterize subunits that are implicated in frequent duplications, as such subunits may host recombination "hotspots" of genomic disorders in 22q11.2.

Gene expression studies at the mRNA level have shown that human melanoma cell lines express CXCR4 and also receptors CCR10 and CCR7 which could be implicated in the frequent metastasis of melanoma to skin and lymph nodes, respectively [ 21].

PI 3-kinase activity is further implicated in carcinogenesis by the frequent inactivation of the tumor suppressor gene PTEN, which encodes the phosphatase that reverses the incorporation of phosphate at the 3′ position of the inositol ring.

In support of our hypothesis, enterococci are among the most frequent pathogens implicated in cases of post-partum emdometritis after cephalosporin prophylaxis [ 21- 23].

Although E. coli was the most frequent uropathogen implicated in community-acquired UTI (being implicated in more than an half of all the UTI), as frequently detected in other studies [ 10, 13, 16, 17], significant differences in relation to the other bacteria involved in the community-acquired UTI were observed relatively to other studies performed at the community level.

While not directly implicated in the case, Kennedy became the frequent butt of jokes on The Tonight Show and other late-night television programs.

These data suggest that mutation of the p16INK4 gene is not a frequent genetic alteration implicated in prostate cancer development.

In Germany, E. coli O157 H7, which is the most frequent EHEC serotype implicated in HUS, is not the only relevant EHEC O157 involved.

We then specifically examined correlations between our lncRNAs and expression of EZH2, a transcriptional repressor, implicated in tumorgenesis in DLBCL due to frequent mutations and with known interactions with lncRNAs [ 22, 23].