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Studies pertaining to trans fatty acids (TFA), which have been implicated in development of chronic diseases, are more relevant in developing countries where nutrition transition is changing traditional habits and practices.
The sirtuin (SIRT /nicotinamide adenine dinucleotide (NAD) system is implicated in development of type 2 diabetes (T2D) and diet-induced obesity, a major risk factor for T2D.
To functionally characterize genes putatively implicated in development of insulin resistance, we work with CRISPR gene perturbations in adipocytes, hepatocytes and skeletal myocytes followed by functional assays relevant to insulin resistance.
Autonomic dysfunction, in particular under-regulation of heart rate (HR) by the baroreflex, is implicated in development of insulin resistance (IR).
Translesion synthesis is a fundamental biological process that enables DNA replication across lesion sites to ensure timely duplication of genetic information at the cost of replication fidelity, and it is implicated in development of cancer drug resistance after chemotherapy.
CD36 facilitates oxidized low density lipoprotein uptake and is implicated in development of atherosclerotic lesions.
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Loss of function of DNA repair genes has been implicated in the development of many types of cancer.
HPV infections are also implicated in the development of other types of carcinomas.
Recently, a growing number of miRNAs have been implicated in the development of NPC.
There are a lot of variables implicated in the development of emotional regulation, including family, school, peer, and genetic factors.
Proteins that contain BRDs have been implicated in the development of a large variety of diseases.
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