Studies pertaining to trans fatty acids (TFA), which have been implicated in development of chronic diseases, are more relevant in developing countries where nutrition transition is changing traditional habits and practices.
Galvanotaxis, the migratory response of cells in response to electrical stimulation, has been implicated in development and wound healing.
The sirtuin (SIRT /nicotinamide adenine dinucleotide (NAD) system is implicated in development of type 2 diabetes (T2D) and diet-induced obesity, a major risk factor for T2D.
D6 proteins have been implicated in development and cellular differentiation.
CD36 facilitates oxidized low density lipoprotein uptake and is implicated in development of atherosclerotic lesions.
POU domain proteins have been implicated in development, replication, growth and cell cycle arrest, and differentiation [4] [6].
Ubiquitously expressed calpain-I (μ-calpain) and calpain-II (m-calpain) proteases are implicated in development of apoptosis.
These latter observations pointed to an association of HERV-W env with specific immune genes but also highlighted its link to processes implicated in development and transcriptional regulation.
Increased expression of FAT/CD36, FATP1, UCP2 and UCP3 have all been implicated in development of lipotoxic heart disease [20], [52], [53].
Importantly, high level of Mcl-1 has been implicated in development and maintenance of both solid tumors and haematological malignancies and contributes to drug resistance [14].
We previously showed that the inactivation of PDZK1 did not affect SR-BI levels in two cell types known to be implicated in development of atherosclerosis, macrophages and endothelial cells [21].
