Sentence examples for implicated in advanced from inspiring English sources
A decade out of grad school, as a young scientist at Genentech, Levinson would help researcher Axel Ullrich clone the HER2 gene implicated in advanced breast cancer; it would become the target for Herceptin.
Activation of MAP kinase signaling pathway has been implicated in advanced and androgen-independent prostate cancers, although formal genetic proof has been lacking.
LGALS3 encoding galectin-3 has been implicated in advanced stage disease [ 30].
A select group of 33 proteins implicated in advanced PCa or disease progression was evaluated by immunohistochemistry (Table 1) on our PCa cohort TMAs.
In this study aiming to find new genetic factors for advanced AMD, we report a genome-wide significant association near FRK/COL10A1 (rs1999930, P = 1.1 × 10−8), a locus not previously implicated in advanced AMD.
Leptin and insulin/IGF-1 are high in obese men (Hoda et al, 2010) and suppress androgen levels, moreover leptin has been implicated in advanced and high-grade prostate cancer in two case control studies (Saglam et al, 2003; Ribeiro et al, 2006).
Brian Helfand, a urologic oncologist with NorthShore University HealthSystem in Evanston, Ill., said researchers there and at Johns Hopkins University are studying three mutations most frequently implicated in localized and advanced prostate cancer and their frequency in whites, African Americans and Asians.
In the last few years, considerable advances have been made in identifying AMD susceptibility genes, in particular those implicated in the development of advanced disease.
Its inhibition by a tumor cell product was implicated in the progression of advanced squamous cell tumors [ 32] suggesting its cytotoxic capability against target cells.
These compounds are inhibitors of aldose reductase, an enzyme that has been implicated in the formation of cataracts in advanced stages of diabetes mellitus.
Factors implicated in the etiology are ultraviolet exposure, advanced age and immunosuppression [2].
