CP26 has been implicated in a study of bTB in wild boar [9] while INRA111 was implicated in a study of footrot in sheep (E. Smith, MS in review).
Co-infection can have clinical consequences, for example, presence of Cryptosporidium spp. has been associated with an increased severity of diarrhoea in T. foetus positive cats [ 13], and enteropathogen interdependence has been implicated in a study examining the effects of fenbendazole treatment in cats with concurrent Giardia spp. and Cryptosporidium spp. infection [ 14].
While correlation of Hsp27 expression with survival rate was observed in some studies [ 24, 25, 28], inverse correlation with survival was implicated in a different study [ 27], and no prognostic significance was observed by other studies [ 23, 26].
Cross-contamination in the feed-production process was also implicated in a recent study by Paul et al. [ 23], in which a spatial analysis of the French feed industry and BSE case data showed that BSE risk in France after a ban on MBM in ruminant feed is spatially linked to the use of MBM in non-ruminant feed.
SPOCK2, also known as Sparc/osteonectin, was implicated, in a recent study, as a discriminator between SpA and healthy controls [ 22] and has been hypothesised to play roles in the regulation and production, assembly, or maintenance of matrix turnover in cartilage [ 36, 37].
Outbreak-associated foods were considered to be confirmed vehicles of transmission if 1) they were statistically implicated in an epidemiologic study, 2) S. Enteritidis was isolated from leftover foods, or 3) if the food item was the only food consumed by all ill persons (this occurred in <10 outbreaks).
59 The role/association of inflammation and CKD was implicated in a cross-sectional study by Lee et al, who studied the interrelationships between elevated C-reactive protein (defined as >3), MetS (NCEP-ATPIII definition), and CKD (eGFR <60 mL/min/1.73 m or albuminuria) in 9,586 subjects without diabetes mellitus or hypertension.
The peak on chromosomal band 14q12 falls within a region implicated in a homozygosity mapping study of intellectual disability (OMIM 611095) (Abou Jamra et al. 2011).
One of these genes, fea2, was implicated in a previous QTL study for kernel row number, a trait that correlated with inflorescence meristem size (Bommert et al. 2013).
Chromosome 10q26 had previously been implicated in a candidate gene study [ 21] that reported aberrant endometrial EMX2 expression in women with endometriosis.
Interestingly, these two TFs were implicated in a transcriptomic profiling study of E. coli exposed to CORM-2 and subsequently mutated (51); deletion of these oxidative stress-sensing regulators increased CORM-2 sensitivity.
