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In 19 of these cases (95%), the implicated component was either plasma or platelets [25].
A fourth implicated component is lipids and a fifth is divalent calcium ions.
In 19 of these cases (95%), the implicated component was either plasma or platelets [ 25].
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Postsynaptic glutamate receptor trafficking in particular has moved into the focus of interest because several independent lines of evidence have implicated components of the protein machinery that regulates AMPA- and NMDA-receptors at the synapse.
There has been no evidence to date of yeast prion proteins being physically associated with any cellular structures, although there are several reports implicating components of the cytoskeleton in the process of [PSI+] prion generation and propagation in yeast [36] [38].
The basic mechanism implicates components involved in chromatin modifications, like histone deacetylases Clr3 (HDAClr6 Clr6 (RPD3), and, especially, Sir2 (which deacetylates H3K9 and H4K16), which is followed by H3K9me by Clr4 protein (a homolog of mammalian proteins SUV39H) (reviewed in [ 81]).
Complex I (NADH ubiquinone oxidoreducatase, EC 1.6.5.3) is the largest and most commonly implicated RC component in human mitochondrial disease.
The cas genes have been implicated as components of a host defense system against invading foreign replicons [70].
Studies in laboratory animals have implicated many components of plant extracts as possible bioactive agents responsible for increasing endogenous testosterone levels and enhancing male sexual behavior.
We therefore directly analyzed the WNT pathway using a list of genes previously implicated as components of this pathway (http://www.stanford.edu/group/nusselab/cgi-bin/wnt/).
The laboratory-generated particles used in our study did not contain metals or organic carbon, both of which have been implicated as components that drive PM health effects.
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