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Further, contributions of specific downstream Ras effectors, such as Raf/MEK/Erk, PI3K/Akt, and upstream Ras activators such as receptor tyrosine kinases have also been implicated by using FTIs.
FA (2 mM) in the 3D-culture revealed significantly higher cytotoxicity than the 2D-culture suggesting that biological significance may be implicated by using either 3D- or 2D-culture model.
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Isolates within these CCs were also implicated by use of spa and SCCmec typing.
The fucose-α(1 2 -glycans have been implicated, by others using animal models, in the molecular mechanisms that underlie neuronal development, learning and memory.
First, we identify genes implicated by each SNP using LD from reference genomes.
Unresolved questions also remain concerning the details of the complex regulatory regimes implicated by the use of such clauses.
Similarly, the Fifth Amendment has been held not to be implicated by the use of undercover Government agents before charges are filed because of the absence of the potential for compulsion.
The traits implicated were also analyzed by using the full likelihood ratio test based LMM (MixABEL::FMM), Grammar- γ, and MixABEL::GWFGLS (which is very similar to OmicABEL) methods.
Therefore, we next verified whether CAD endonuclease was implicated in SAHA effects by using two shRNAs against CAD mRNA that efficiently downregulate CAD protein levels in U251-MG cells.
Virus-like particles have been observed[4]; however, efforts to implicate an infectious agent by using culture, subtractive cloning and consensus polymerase chain reaction for detection of other viruses found in salmon aquaculture including infectious pancreatic necrosis virus, salmonid alphavirus, infectious salmon anemia virus have been unsuccessful.
We next sought to validate microglial cell death pathways, which were implicated by IPA network analysis, and used caspases as a protein marker for cell death induction.
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